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Cyclin E1 Antikörper (pThr77) (AbBy Fluor® 350)

CCNE1 Reaktivität: Human WB, FACS, IF (cc) Wirt: Kaninchen Polyclonal AbBy Fluor® 350

Produktnummer ABIN878416

Datenblatt (PDF)

Target Alle Cyclin E1 (CCNE1) Antikörper anzeigen

Cyclin E1 (CCNE1)
Bindungsspezifität
26

16

13

11

9

8

7

6

5

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pThr77
Reaktivität
135

35

31

3

2

2

2
Human
Wirt
110

24

1
Kaninchen
Passende Sekundärantikörper
Klonalität
103

32
Polyklonal
Konjugat
76

7

5

4

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

1

1
Dieser Cyclin E1 Antikörper ist konjugiert mit AbBy Fluor® 350
Applikation
89

43

41

37

28

27

18

13

9

6

3

3

3

2

2

1

1

1

1

1

1
Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))

Kreuzreaktivität

Human

Homologie

Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung

Purified by Protein A.

Immunogen

KLH conjugated synthetic phosphopeptide derived from human Cyclin E around the phosphorylation site of Thr77

Isotyp

IgG

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anti-Cyclin E1 (CCNE1) (AA 1-100) antibody
CCNE1 Reaktivität: Human IHC, ELISA, FACS Wirt: Maus Monoclonal 1C8D4 unconjugated

anti-Cyclin E1 (CCNE1) (AA 307-410) antibody
CCNE1 Reaktivität: Human ELISA, FACS Wirt: Maus Monoclonal 5F8C5 unconjugated

anti-Cyclin E1 (CCNE1) (AA 375-411) antibody
CCNE1 Reaktivität: Human, Maus, Ratte WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Cyclin E1 (CCNE1) (AA 1-410) antibody
CCNE1 Reaktivität: Human WB, PLA Wirt: Kaninchen Polyclonal unconjugated

anti-Cyclin E1 (CCNE1) (AA 307-410) antibody
CCNE1 Reaktivität: Human, Maus Wirt: Maus Monoclonal unconjugated

anti-Cyclin E1 (CCNE1) (Thr395) antibody
CCNE1 Reaktivität: Human WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Cyclin E1 (CCNE1) antibody
CCNE1 Reaktivität: Human IHC, ELISA, IF Wirt: Kaninchen Monoclonal 3A5 unconjugated Recombinant Antibody

anti-Cyclin E1 (CCNE1) (AA 373-402), (C-Term) antibody
CCNE1 Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB07335 unconjugated

anti-Cyclin E1 (CCNE1) (AA 1-410) antibody
CCNE1 Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated

Applikationshinweise

FCM 1:20-100
IF(ICC) 1:50-200

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 μg/μL

Buffer

Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit

12 months
Target

Cyclin E1 (CCNE1)

Andere Bezeichnung

Cyclin E (CCNE1 Produkte)

Hintergrund

Synonyms: CCNE 1, CCNE,CCNE1,Cyclin E1 antibody Cyclin Es,Cyclin Et,CyclinE, G1/S specic cyclin E, CCNE1_HUMAN.
Background: Cyclin E is a regulatory subunit of Cdk2 and controls G1 / S transition during the mammalian cell cycle. Multiple isoforms of Cyclin E are only expressed in tumors but not in normal tissue, suggesting a post transcriptional regulation of Cyclin E. In vitro analyses indicated that these truncated variant isoforms of Cyclin E are able to phosphorylate histone H1. Alterations in the Cyclin E protein have been implicated as indicators of worse prognosis in various cancers.

Molekulargewicht

47kDa

Gen-ID

898

Pathways

Zellzyklus, Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Mitotic G1-G1/S Phases