FRMD6 Antikörper (AA 51-150)

Produktnummer ABIN873129

Dieses Anti-FRMD6-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von FRMD6 in WB, ELISA, IF (cc), IF (p), IHC (fro) und IHC (p). Geeignet für Human.

Kurzübersicht für FRMD6 Antikörper (AA 51-150) (ABIN873129)

Target: FRMD6 (FERM Domain Containing 6 (FRMD6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FRMD6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-FRMD6 Antikörper

Bindungsspezifität: AA 51-150

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FRMD6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu FRMD6

Target: FRMD6 (FERM Domain Containing 6 (FRMD6))

Andere Bezeichnung: Frmd6

Hintergrund:

Synonyms: EX1, Willin, C14orf31, c14_5320, FERM domain-containing protein 6, FRMD6

Background: FERM domains are roughly 150 amino acids in length and are found in a number of cytoskeletal-associated proteins such as Ezrin, Radixin, Moesin and 4.1 (erythrocyte membrane protein band 4.1), where they provide a link between cytoskeletal signals and membrane dynamics. FRMD6 (FERM domain containing 6), also known as EX1 or Willin, is a 622 amino acid cytoplasmic and peripheral membrane protein that can colocalize with Actin and exists as three alternatively spliced isoforms. Containing one FERM domain within its N-terminus, FRMD6 binds phospholipids and is encoded by a gene mapping to human chromosome 14, which houses over 700 genes and comprises nearly 3.5 % of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD).

Gen-ID: 122786

UniProt: Q96NE9