FRMD6 Antikörper (AA 51-150)

Produktnummer ABIN873129

Dieser Anti-FRMD6 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von FRMD6 in WB, ELISA, IF (cc), IF (p), IHC (fro) und IHC (p). Geeignet für Human.

Kurzübersicht für FRMD6 Antikörper (AA 51-150) (ABIN873129)

Target: FRMD6 (FERM Domain Containing 6 (FRMD6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FRMD6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-FRMD6 Antikörper

Bindungsspezifität: AA 51-150

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FRMD6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu FRMD6

Target: FRMD6 (FERM Domain Containing 6 (FRMD6))

Andere Bezeichnung: Frmd6

Hintergrund:

Synonyms: EX1, Willin, C14orf31, c14_5320, FERM domain-containing protein 6, FRMD6

Background: FERM domains are roughly 150 amino acids in length and are found in a number of cytoskeletal-associated proteins such as Ezrin, Radixin, Moesin and 4.1 (erythrocyte membrane protein band 4.1), where they provide a link between cytoskeletal signals and membrane dynamics. FRMD6 (FERM domain containing 6), also known as EX1 or Willin, is a 622 amino acid cytoplasmic and peripheral membrane protein that can colocalize with Actin and exists as three alternatively spliced isoforms. Containing one FERM domain within its N-terminus, FRMD6 binds phospholipids and is encoded by a gene mapping to human chromosome 14, which houses over 700 genes and comprises nearly 3.5 % of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD).

Gen-ID: 122786

UniProt: Q96NE9