MME Antikörper (AA 6-10)
Kurzübersicht für MME Antikörper (AA 6-10) (ABIN871515)
Target
Alle MME Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 6-10
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Spezifität
- The antibody detects endogenous level of total CD10 protein.
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Aufreinigung
- Affinity purified
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Immunogen
- Peptide sequence around AA 6-10 (S-Q-M-D-I) derived from Human CD10. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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Applikationshinweise
- Western blotting: 1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- MME (Membrane Metallo-Endopeptidase (MME))
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Andere Bezeichnung
- CD10
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Substanzklasse
- Chemical
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Hintergrund
- Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers.
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Molekulargewicht
- 100 kDa
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Gen-ID
- 4311
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NCBI Accession
- NP_000893
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UniProt
- P08473
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Pathways
- RTK Signalweg, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
Target
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