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MME Antikörper (AA 6-10)

MME Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated

Produktnummer ABIN871686

Datenblatt (PDF)

Target Alle MME Antikörper anzeigen

MME (Membrane Metallo-Endopeptidase (MME))
Bindungsspezifität
16

14

9

8

8

7

7

7

6

6

5

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 6-10
Reaktivität
208

57

50

3

2

2

2

2

2

1

1

1

1
Human, Maus, Ratte
Wirt
109

104

2
Kaninchen
Passende Sekundärantikörper
Klonalität
109

105

2
Polyklonal
Konjugat
105

19

18

14

9

6

5

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser MME Antikörper ist unkonjugiert
Applikation
132

96

80

69

38

28

21

20

13

13

10

8

5

5

5

3

2

2

1

1

1

1

1
Western Blotting (WB)

Spezifität

The antibody detects endogenous level of total CD10 protein.

Aufreinigung

Affinity purified

Immunogen

Peptide sequence around AA 6-10 (S-Q-M-D-I) derived from Human CD10. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

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anti-Membrane Metallo-Endopeptidase (MME) (AA 52-352) antibody
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anti-Membrane Metallo-Endopeptidase (MME) (AA 382-538) antibody
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anti-Membrane Metallo-Endopeptidase (MME) (AA 501-600) antibody
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anti-Membrane Metallo-Endopeptidase (MME) (AA 286-428) antibody
MME Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

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anti-Membrane Metallo-Endopeptidase (MME) (AA 297-483) antibody
MME Reaktivität: Human WB, IHC, ELISA, StM, Coat Wirt: Maus Monoclonal MME-1892 unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 52-750) antibody
MME Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

Western blotting: 1:500

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 mg/mL

Buffer

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C/-20 °C

Informationen zur Lagerung

Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target

MME (Membrane Metallo-Endopeptidase (MME))

Andere Bezeichnung

CD10 (MME Produkte)

Synonyme

CALLA antikoerper, CD10 antikoerper, NEP antikoerper, SFE antikoerper, 6030454K05Rik antikoerper, C85356 antikoerper, Nep antikoerper, neprilysin antikoerper, membrane metalloendopeptidase antikoerper, membrane metallo endopeptidase antikoerper, membrane metallo-endopeptidase antikoerper, MME antikoerper, Mme antikoerper

Substanzklasse

Chemical

Hintergrund

Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers.

Molekulargewicht

100 kDa

Gen-ID

4311

NCBI Accession

NP_000893

UniProt

P08473

Pathways

RTK Signalweg, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration