Der Kaninchen Polyklonal anti-MME Antikörper (ABIN871686) detektiert spezifisch MME in WB.
Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte und Maus.
The antibody detects endogenous level of total CD10 protein.
Aufreinigung
Affinity purified
Immunogen
Peptide sequence around AA 6-10 (S-Q-M-D-I) derived from Human CD10. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target
MME
(Membrane Metallo-Endopeptidase (MME))
Andere Bezeichnung
CD10
Substanzklasse
Chemical
Hintergrund
Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers.