Complement C4d Antikörper (Internal Region)

Produktnummer ABIN870587

Produktdetails anti-Complement C4d Antikörper

Target: Complement C4d (C4d) (Complement Component C4d (C4d))

Bindungsspezifität: Internal Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Complement C4d Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: C4d complement

Immunogen: Peptide derived from internal sequence of human C4.

Klon: A24-T

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: 1:100 - 200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 20 mM Tris-HCI, pH 8.0, Stabilizer: 20 mg/ml BSA, Preservative: 0.05% sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: +2 °C to +8 °C

Details zu Complement C4d

Target: Complement C4d (C4d) (Complement Component C4d (C4d))

Andere Bezeichnung: C4d complement (C4d Produkte)

Hintergrund: C4d is a split product of the complement C4 and its deposition serves as a sensitive and specific marker for antibody mediated rejection (AMR) of the transplanted organs. AMR is one of the most important adverse events after organ transplantation and if untreated, leads to significant graft loss. During AMR, C4d binds covalently to the target structures, which makes it easy to detect with corresponding antibodies. Currently, all renal transplant biopsies and biopsies from other organs as well, are required to stain with C4d antibody.

UniProt: P0C0L4