PERK Antikörper
Kurzübersicht für PERK Antikörper (ABIN865515)
Target
Alle PERK (EIF2AK3) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Aufreinigung
- Ascitic fluid
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Immunogen
- Purified recombinant fragment of human EIF2AK3 expressed in E. Coli.
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Isotyp
- IgG1
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Applikationshinweise
- WB: 1/500 - 1/2000, ELISA: Propose dilution 1/10000.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 100g/100l
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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- PERK (EIF2AK3) (Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3))
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Andere Bezeichnung
- EIF2AK3
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Hintergrund
- The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. Synonyms: PAX8
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Molekulargewicht
- 125kDa
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Gen-ID
- 9451
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Pathways
- Hormone Transport, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Unfolded Protein Response
Target
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