Dieser Maus Monoklonal Antikörper detektiert spezifisch PDPK1 in WB, IHC, ELISA, IF und FACS. Es zeigt Reaktivität gegenüber Proben von Human, Ratte und Affe.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Target
PDPK1
(3-phosphoinositide Dependent Protein Kinase-1 (PDPK1))
Andere Bezeichnung
PDK1
Hintergrund
Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation.. Tissue specificity: Expressed predominantly in the heart. Synonyms: PDK1