Aktivieren Sie Javascript in Ihrem Browser, um unsere Webseite optimal zu nutzen.

PDPK1 Antikörper (AA 1-150)

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-PDPK1 Antikörper wird verwendet zum Nachweis von PDPK1 in Proben von Human. Er wurde validiert für WB und IF.

Immunofluorescence analysis of PC-12 cells using PDK1/PDHK1 Rabbit pAb (ABIN3015351, ABIN3015352, ABIN1681301, ABIN5663787 and ABIN6214001) at dilution of 1:100 (40x lens). (PDPK1 Antikörper (AA 1-150))

Western blot analysis of extracts of various cell lines, using PDK1/PDHK1 antibody (ABIN3015351, ABIN3015352, ABIN1681301, ABIN5663787 and ABIN6214001) at 1:1000 dilution. (PDPK1 Antikörper (AA 1-150))

Western blot analysis of extracts of HepG2 cells, using PDK1/PDHK1 antibody (ABIN3015351, ABIN3015352, ABIN1681301, ABIN5663787 and ABIN6214001) at 1:1000 dilution. (PDPK1 Antikörper (AA 1-150))

Immunofluorescence analysis of NIH/3T3 cells using PDK1/PDHK1 Rabbit pAb (ABIN3015351, ABIN3015352, ABIN1681301, ABIN5663787 and ABIN6214001) at dilution of 1:100 (40x lens). (PDPK1 Antikörper (AA 1-150))

5 Abbildungen

(1 reference)

Produktnummer ABIN5663787

320,00 €

Zzgl. Versandkosten 20,00 € und MwSt

Lieferung nach: Deutschland

Lieferung in 7 bis 9 Werktagen

Kurzübersicht für PDPK1 Antikörper (AA 1-150) (ABIN5663787)

Target

Alle PDPK1 Antikörper anzeigen

PDPK1 (3-phosphoinositide Dependent Protein Kinase-1 (PDPK1))

Reaktivität

Human

Wirt

Kaninchen

Klonalität

Polyklonal

Konjugat

Dieser PDPK1 Antikörper ist unkonjugiert

Applikation

Western Blotting (WB), Immunofluorescence (IF)

Discover our top product PDPK1 Primärantikörper

Bindungsspezifität
29

24

15

15

15

15

8

6

6

4

4

4

4

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1-150

Sequenz

MRLARLLRGA ALAGPGPGLR AAGFSRSFSS DSGSSPASER GVPGQVDFYA RFSPSPLSMK QFLDFGSVNA CEKTSFMFLR QELPVRLANI MKEISLLPDN LLRTPSVQLV QSWYIQSLQE LLDFKDKSAE DAKAIYDFTD TVIRIRNRHN

Kreuzreaktivität

Human, Maus, Ratte

Produktmerkmale

Polyclonal Antibodies

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human PDK1/PDHK1 (NP_002601.1).

Isotyp

IgG
anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) (pSer241) antibody
PDPK1 Reaktivität: Human, Maus, Ratte WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) (AA 150-429) antibody
PDPK1 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated

anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) (AA 1-429) antibody
PDPK1 Reaktivität: Human WB, PLA Wirt: Maus Polyclonal unconjugated

anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) (AA 457-556) antibody
PDPK1 Reaktivität: Human, Maus, Ratte, Affe WB, IHC, ELISA, ICC, FACS Wirt: Maus Monoclonal 7E4G11 unconjugated

anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) antibody
PDPK1 Reaktivität: Human, Ratte, Affe WB, IHC, ELISA, ICC, FACS Wirt: Maus Monoclonal 4A11 unconjugated

anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) (AA 524-556), (C-Term) antibody
PDPK1 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated

anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) (AA 83-338) antibody
PDPK1 Reaktivität: Human WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) (AA 457-556) antibody
PDPK1 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 2E2 unconjugated

anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) antibody
KD Validated PDPK1 Reaktivität: Human WB, FACS Wirt: Kaninchen Monoclonal 24GB5425 unconjugated Recombinant Antibody

anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) (pTyr373), (pTyr376) antibody
PDPK1 Reaktivität: Human, Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

WB,1:500 - 1:1000,IF,1:50 - 1:200

Beschränkungen

Nur für Forschungszwecke einsetzbar
Buffer

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20°C. Avoid freeze / thaw cycles.
Qin, Zheng, Zhou, Ou, Huang, Yan, Qin, Yang, Su, Bai, Guo, Lin: "Tsc1 deficiency impairs mammary development in mice by suppression of AKT, nuclear ERα, and cell-cycle-driving proteins." in: Scientific reports, Vol. 6, pp. 19587, (2017) (PubMed).
Target

PDPK1 (3-phosphoinositide Dependent Protein Kinase-1 (PDPK1))

Andere Bezeichnung

PDK1

Hintergrund

Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene.,PDK1,Cancer,Signal Transduction,PI3K-Akt Signaling Pathway,Protein Kinase C Signaling Pathway,Endocrine & Metabolism,Carbohydrate metabolism,Warburg Effect,Immunology & Inflammation,T Cell Receptor Signaling Pathway,NF-kB Signaling Pathway,Kinase of Akt,PDK1

Molekulargewicht

49 kDa/51 kDa

Gen-ID

5163

UniProt

Q15118

Pathways

PI3K-Akt Signalweg, T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Regulation of Cell Size, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals