Aurora A Antikörper

Produktnummer ABIN865471

Produktdetails anti-Aurora A Antikörper

Target: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Reaktivität: Human, Ratte, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Aurora A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human AURKA expressed in E. Coli.

Klon: 1F8

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 1/500 - 1/2000, IHC: 1/200-1/1000, FC: 1/200-1/400, ELISA: Propose dilution 1/10000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100g/100l

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu Aurora A

Target: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Andere Bezeichnung: AURKA (AURKA Produkte)

Hintergrund: Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment. Tissue specificity: Highly expressed in testis and weakly in skeletal muscle, thymus and spleen. Also highly expressed in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines. Synonyms: AIK, ARK1, AURA, BTAK, STK6, STK7, STK15, AURORA2, MGC34538, AURKA

Molekulargewicht: 48kDa

Gen-ID: 6790

Pathways: Zellzyklus, Asymmetric Protein Localization