GRIA2 Antikörper (pSer880) (Cy7)

Produktnummer ABIN800904

Dieser Anti-GRIA2-Antikörper ist ein Kaninchen-Polyklonal-Antikörper zum Nachweis von GRIA2 in WB, IF (p) und IF (cc). Geeignet für Human.

Kurzübersicht für GRIA2 Antikörper (pSer880) (Cy7) (ABIN800904)

Target: GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRIA2 Antikörper ist konjugiert mit Cy7

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Produktdetails anti-GRIA2 Antikörper (Cy7)

Bindungsspezifität: pSer880

Homologie: Human,Mouse,Rat,Cow,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human Gria2 around the phosphorylation site of Ser880

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu GRIA2

Target: GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Andere Bezeichnung: Gria2

Hintergrund:

Synonyms: Glutamate receptor 2 PrecursorSer880, Gria2, Glur-2, GluR-B, Glur2, GluR-2, GluR-K2, Glutamate receptor 2, Glutamate receptor ionotropic, AMPA 2, glutamate receptor, ionotropic, N-methyl D-aspartate 1, NMDA receptor subunit , AMPA-selective glutamate receptor 2.

Background: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate(AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, Gria1-4. The subunit encoded by this gene (Gria2) is subject to RNA editing(CAG->CGG, Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Alternative splicing, resulting in transcript variants encoding different isoforms, (including the flip and flop isoforms that vary in their signal transduction properties), has been noted for this gene.

Gen-ID: 2891

Pathways: PI3K-Akt Signalweg