ENOS Antikörper (AA 1181-1194)

Produktnummer ABIN784232

Der Kaninchen Polyklonal Anti-ENOS-Antikörper wurde für WB und IHC (p) validiert. Er ist geeignet, ENOS in Proben von Human, Ratte, Maus, Schwein, Rind (Kuh), Hund und Meerschweinchen zu detektieren.

Kurzübersicht für ENOS Antikörper (AA 1181-1194) (ABIN784232)

Target: ENOS (NOS3) (Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3))

Reaktivität: Human, Ratte, Maus, Schwein, Rind (Kuh), Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ENOS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-ENOS Antikörper

Bindungsspezifität: AA 1181-1194

Sequenz: CQERQLRGAV PWAFD Remarks: The immunizing sequence has 10/11 identical amino acids in Mouse, Guinea Pig, Bovine, Porcine, Rat and Canine. Antigen Modificati on: aa1181-1194

Spezifität: Recognizes eNOS/NOS III, Mr ~135 kDa.

Kreuzreaktivität (Details): Species reactivity (expected):Bovine, Dog, Guinea pig, Mouse, Porcine, Rat.
Species reactivity (tested):Human.

Aufreinigung: Protein A Chromatography.

Immunogen: kLH-conjugated, synthetic peptide corresponding to amino acids 1181-1194 of Human eNOS/NOS III.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.6, 0.07 % Sodium Azide, before the addition of Glycerol to 30 %.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu ENOS

Target: ENOS (NOS3) (Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3))

Andere Bezeichnung: NOS3

Hintergrund: Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Multiple transcript variants encoding different isoforms have been found for this gene.Synonyms: Constitutive NOS, EC-NOS, Endothelial NOS, NOS type III, Nitric oxide synthase, eNOS, endothelial

Gen-ID: 4846

NCBI Accession: NP_000594

Pathways: ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Response to Molecule of Bacterial Origin, Myometrial Relaxation and Contraction, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling