ENOS Antikörper (AA 1-120)

Produktnummer ABIN3022122

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ENOS in WB und IF. Es zeigt Reaktivität gegenüber Proben von Human. Es wurde in 2+ Publikationen zitiert.

Kurzübersicht für ENOS Antikörper (AA 1-120) (ABIN3022122)

Target: ENOS (NOS3) (Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ENOS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-ENOS Antikörper

Bindungsspezifität: AA 1-120

Sequenz: MGNLKSVAQE PGPPCGLGLG LGLGLCGKQG PATPAPEPSR APASLLPPAP EHSPPSSPLT QPPEGPKFPR VKNWEVGSIT YDTLSAQAQQ DGPCTPRRCL GSLVFPRKLQ GRPSPGPPAP

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human eNOS (NP_000594.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-ENOS Antikörper (ABIN3022122)

Luo, Dan Wang, Luo, Zhu, Wang, Ning, Li, Ma, Yang, Jin, Huang, Meng, Li: "Caveolin 1-related autophagy initiated by aldosterone-induced oxidation promotes liver sinusoidal endothelial cells defenestration." in: Redox biology, Vol. 13, pp. 508-521, (2018) (PubMed).

Luo, Wang, Zhu, Wang, You, Ning, Li, Jin, Huang, Hu, Chen, Meng, Li: "Autophagic degradation of caveolin-1 promotes liver sinusoidal endothelial cells defenestration." in: Cell death & disease, Vol. 9, Issue 5, pp. 576, (2018) (PubMed).

Details zu ENOS

Target: ENOS (NOS3) (Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3))

Andere Bezeichnung: NOS3

Hintergrund: Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Alternative splicing and the use of alternative promoters results in multiple transcript variants.,NOS3,ECNOS,eNOS,Cancer,Signal Transduction,PI3K-Akt Signaling Pathway,Cell Biology & Developmental Biology,Endocrine & Metabolism,AMPK Signaling Pathway,Neuroscience,Cardiovascular,Angiogenesis,Blood,Hypoxia,NOS3

Molekulargewicht: 67 kDa/68 kDa/133 kDa

Gen-ID: 4846

UniProt: P29474

Pathways: ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Response to Molecule of Bacterial Origin, Myometrial Relaxation and Contraction, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling