ENOS Antikörper

Produktnummer ABIN784153

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ENOS in WB. Er zeigt eine Reaktivität gegenüber Human, Ratte, Maus, Schwein, Rind (Kuh), Schaf, Affe und Pferd.

Kurzübersicht für ENOS Antikörper (ABIN784153)

Target: ENOS (NOS3) (Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3))

Reaktivität: Human, Ratte, Maus, Schwein, Rind (Kuh), Schaf, Affe, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ENOS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ENOS Antikörper

Spezifität: The antibody recognizes 140 kDa eNOS.

Kreuzreaktivität (Details): Species reactivity (expected):Pig, Horse, Sheep, Cattle, Monkey.
Species reactivity (tested):Human, Mouse, and Rat.

Aufreinigung: Affinity Chromatography.

Immunogen: Synthetic peptide surrounding amino acid 602 of Rat eNOS

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 30 % Glycerol, 0.5 % BSA, and 0.01 % Thimerosal.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody at -20 °C. For long term storage aliquot and freeze at -70 °C.

Details zu ENOS

Target: ENOS (NOS3) (Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3))

Andere Bezeichnung: NOS3

Hintergrund: ENOS (Endothelial nitric-oxide synthase) is an important enzyme in the cardiovascular system. eNOS is regulated by phosphorylation at multiple sites. The two most thoroughly studied sites are the activation site Ser1177 and the inhibitory site Thr495. Several protein kinases including Akt/PKB, PKA and AMPK activate eNOS by phosphorylating Ser1177 in response to various stimuli. In contrast, bradykinin and hydrogen peroxide activate eNOS activity by promoting Thr495 dephosphorylation.Synonyms: Constitutive NOS, EC-NOS, Endothelial NOS, NOS type III, Nitric oxide synthase, eNOS, endothelial

Gen-ID: 4846

NCBI Accession: NP_000594

Pathways: ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Response to Molecule of Bacterial Origin, Myometrial Relaxation and Contraction, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling