RGS17 Antikörper (AA 148-160)
Kurzübersicht für RGS17 Antikörper (AA 148-160) (ABIN784001)
Target
Alle RGS17 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 148-160
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Spezifität
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Recognizes RGS17.
Cellular Localization: Membrane, Lipid-anchor, Nucleus, Cytoplasm. -
Kreuzreaktivität (Details)
- Species reactivity (tested):Human.
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Aufreinigung
- Antigen-Affinity Chromatography.
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Immunogen
- Synthetic peptide contain a sequence corresponding to a region within amino acids 148 and 160 of Human RGS17.
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1.0 mg/mL
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Buffer
- 1xPBS, 1 % BSA, 20 % Glycerol ( pH 7) containing 0.01 % Thimerosal as a preservative.
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Konservierungsmittel
- Thimerosal (Merthiolate)
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Vorsichtsmaßnahmen
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store the antibody undiluted (in aliquots) at -20 °C.
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- RGS17 (Regulator of G-Protein Signaling 17 (RGS17))
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Andere Bezeichnung
- RGS17
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Hintergrund
- This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.Synonyms: RGS-17, RGSZ2, Regulator of G-protein signaling 17
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Gen-ID
- 26575, 9606
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Pathways
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
Target
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