RGS17 Antikörper (AA 70-150)
Kurzübersicht für RGS17 Antikörper (AA 70-150) (ABIN7231022)
Target
Alle RGS17 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 70-150
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Verwendungszweck
- Rabbit Anti-RGS17 Polyclonal Antibody
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Spezifität
- The antibody detects endogenous levels of RGS17 protein
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Synthesized peptide derived from part region of human RGS17 protein at AA range: 70-150
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Haltbarkeit
- 12 months
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- RGS17 (Regulator of G-Protein Signaling 17 (RGS17))
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Andere Bezeichnung
- RGS17
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Hintergrund
- Regulator of G-protein signaling 17, RGS17RGS17 (Regulator Of G Protein Signaling 17) encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.
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Molekulargewicht
- 23kD
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Gen-ID
- 26575
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UniProt
- Q9UGC6
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Pathways
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
Target
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