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RGS17 Antikörper (N-Term)

RGS17 Reaktivität: Human, Maus WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6264721
  • Target Alle RGS17 Antikörper anzeigen
    RGS17 (Regulator of G-Protein Signaling 17 (RGS17))
    Bindungsspezifität
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 14
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Maus
    Wirt
    • 10
    • 2
    • 1
    • 1
    Kaninchen
    Klonalität
    • 13
    • 1
    Polyklonal
    Konjugat
    • 14
    Dieser RGS17 Antikörper ist unkonjugiert
    Applikation
    • 13
    • 5
    • 4
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Spezifität
    RGS17 Antibody detects endogenous levels of total RGS17.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human RGS17, corresponding to a region within N-terminal amino acids.
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    RGS17 (Regulator of G-Protein Signaling 17 (RGS17))
    Andere Bezeichnung
    RGS17 (RGS17 Produkte)
    Synonyme
    RGS17 antikoerper, zgc:92802 antikoerper, MGC179306 antikoerper, RGS-17 antikoerper, RGSZ2 antikoerper, hRGS17 antikoerper, 6430507P11Rik antikoerper, Rgsz2 antikoerper, regulator of G protein signaling 17 antikoerper, regulator of G-protein signaling 17 antikoerper, RGS17 antikoerper, Rgs17 antikoerper, rgs17 antikoerper
    Hintergrund

    Description: Regulates G protein-coupled receptor signaling cascades, including signaling via muscarinic acetylcholine receptor CHRM2 and dopamine receptor DRD2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:15096504). Binds selectively to GNAZ and GNAI2 subunits, accelerates their GTPase activity and regulates their signaling activities. Negatively regulates mu-opioid receptor-mediated activation of the G-proteins (By similarity).

    Gene: RGS17

    Molekulargewicht
    24 kDa
    Gen-ID
    26575
    UniProt
    Q9UGC6
    Pathways
    Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
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