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GFAP Antikörper

GFAP Reaktivität: Human, Ratte, Maus, Rind (Kuh), Huhn, Meerschweinchen, Schaf, Affe, Hamster IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN783875
  • Target Alle GFAP Antikörper anzeigen
    GFAP (Glial Fibrillary Acidic Protein (GFAP))
    Reaktivität
    • 290
    • 173
    • 169
    • 51
    • 50
    • 33
    • 31
    • 11
    • 10
    • 8
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Ratte, Maus, Rind (Kuh), Huhn, Meerschweinchen, Schaf, Affe, Hamster
    Wirt
    • 191
    • 143
    • 12
    • 2
    • 2
    • 2
    Kaninchen
    Klonalität
    • 191
    • 160
    • 1
    Polyklonal
    Konjugat
    • 172
    • 27
    • 23
    • 17
    • 11
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Dieser GFAP Antikörper ist unkonjugiert
    Applikation
    • 277
    • 135
    • 97
    • 80
    • 76
    • 57
    • 44
    • 28
    • 26
    • 26
    • 23
    • 18
    • 13
    • 8
    • 8
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Spezifität
    This antibody recognizes Glial Fibrillary Acidic Protein (GFAP). Cellular localization: Cytoplasmic.
    Kreuzreaktivität (Details)
    Species reactivity (expected):Human, Mouse, Rat, Sheep, Monkey, Hamster, Guinea pig and Chicken.
    Species reactivity (tested):Bovine.
    Aufreinigung
    Purified
    Immunogen
    GFAP isolated from cow spinal cord. Genename: GFAP
    Isotyp
    IgG
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  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    10 mM PBS, pH 7.4, 0.09 % Sodium Azide, 0.2 % BSA
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C.
  • Target
    GFAP (Glial Fibrillary Acidic Protein (GFAP))
    Andere Bezeichnung
    GFAP (GFAP Produkte)
    Hintergrund
    Glial fibrillary acidic protein (GFAP) is an intermediate-filament (IF) protein that is highly specific for cells of astroglial lineage, although its tissue-specific role is speculative. GFAP has been located in rat kidney glomeruli and peritubular fibroblasts, leydig cells of testis, skin keratinocytes, osteocytes of bones, chondrocytes of epiglottis, bronchus, and stellate-shaped cells of the pancreas and liver. Its expression is essential for normal white matter architecture and blood-brain barrier integrity, and its absence leads to late-onset CNS dysmyelination. GFAP has also been shown to play a role in mitosis by adjusting the filament network present in the cell. During mitosis, there is an increase in the amount of phosphorylated GFAP, and a movement of this modified protein to the cleavage furrow.Synonyms: Glial Fibrillary Acidic Protein
    Gen-ID
    2670
    NCBI Accession
    NP_001124491
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