GFAP Antikörper

Produktnummer ABIN783875

Der Kaninchen-Polyklonal Anti-GFAP-Antikörper wurde für IHC (p) validiert. Er ist geeignet zum Nachweis von GFAP in Proben aus Human, Ratte, Maus, Rind (Kuh), Huhn, Meerschweinchen, Schaf, Affe und Hamster. }

Kurzübersicht für GFAP Antikörper (ABIN783875)

Target: GFAP (Glial Fibrillary Acidic Protein (GFAP))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Huhn, Meerschweinchen, Schaf, Affe, Hamster

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GFAP Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-GFAP Antikörper

Spezifität: This antibody recognizes Glial Fibrillary Acidic Protein (GFAP). Cellular localization: Cytoplasmic.

Kreuzreaktivität (Details): Species reactivity (expected):Human, Mouse, Rat, Sheep, Monkey, Hamster, Guinea pig and Chicken.
Species reactivity (tested):Bovine.

Aufreinigung: Purified

Immunogen: GFAP isolated from cow spinal cord. Genename: GFAP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 10 mM PBS, pH 7.4, 0.09 % Sodium Azide, 0.2 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu GFAP

Target: GFAP (Glial Fibrillary Acidic Protein (GFAP))

Andere Bezeichnung: GFAP

Hintergrund: Glial fibrillary acidic protein (GFAP) is an intermediate-filament (IF) protein that is highly specific for cells of astroglial lineage, although its tissue-specific role is speculative. GFAP has been located in rat kidney glomeruli and peritubular fibroblasts, leydig cells of testis, skin keratinocytes, osteocytes of bones, chondrocytes of epiglottis, bronchus, and stellate-shaped cells of the pancreas and liver. Its expression is essential for normal white matter architecture and blood-brain barrier integrity, and its absence leads to late-onset CNS dysmyelination. GFAP has also been shown to play a role in mitosis by adjusting the filament network present in the cell. During mitosis, there is an increase in the amount of phosphorylated GFAP, and a movement of this modified protein to the cleavage furrow.Synonyms: Glial Fibrillary Acidic Protein

Gen-ID: 2670

NCBI Accession: NP_001124491