STAU1/Staufen Antikörper (C-Term)
Kurzübersicht für STAU1/Staufen Antikörper (C-Term) (ABIN783741)
Target
Alle STAU1/Staufen (STAU1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Spezifität
- This antibody detects STAU / STAU1 at C-term.
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Kreuzreaktivität (Details)
- Species reactivity (tested):Human, mouse, rat
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Aufreinigung
- Affinity chromatography purified via peptide column
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Immunogen
- 15 amino acid peptide near the carboxy terminus of human STAU1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- PBS containing 0.02 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- STAU1/Staufen (STAU1) (Staufen Double-Stranded RNA Binding Protein 1 (STAU1))
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Andere Bezeichnung
- STAU / STAU1
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Hintergrund
- STAU1 is a member of a family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human STAU1 also contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. STAU1 has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER. STAU1 is also known to interact with influenza ribonucleoproteins NS1, NP, and PA and is required for efficient viral replication.Synonyms: Double-stranded RNA-binding protein Staufen homolog 1, FLJ25010, staufen homolog 1
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Gen-ID
- 6780
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NCBI Accession
- NP_001032405
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UniProt
- O95793
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Pathways
- Asymmetric Protein Localization
Target
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