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STAU1/Staufen Antikörper (C-Term)

STAU1 Reaktivität: Human, Maus WB, IP Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2854568
  • Target Alle STAU1/Staufen (STAU1) Antikörper anzeigen
    STAU1/Staufen (STAU1) (Staufen Double-Stranded RNA Binding Protein 1 (STAU1))
    Bindungsspezifität
    • 10
    • 8
    • 6
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 65
    • 32
    • 31
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    Human, Maus
    Wirt
    • 61
    • 4
    Kaninchen
    Klonalität
    • 53
    • 12
    Polyklonal
    Konjugat
    • 30
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser STAU1/Staufen Antikörper ist unkonjugiert
    Applikation
    • 54
    • 21
    • 14
    • 13
    • 9
    • 9
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    Kreuzreaktivität
    Rhesusaffen
    Kreuzreaktivität (Details)
    Rhesus Monkey (100 %)
    Produktmerkmale
    Rabbit Polyclonal antibody to Staufen (staufen, RNA binding protein, homolog 1 (Drosophila))
    Staufen antibody
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the C-terminus region of human Staufen. The exact sequence is proprietary.
    Isotyp
    IgG
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  • Applikationshinweise
    Suggested dilution Reference Immunoprecipitation 1:500-1:3000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceImmunoprecipitation1:500-1:3000* Western blot1:500-1:3000*
    Kommentare

    Positive Control: 293T , A431 , H1299 , HepG2 , Molt-4 , Raji , Neuro2A , 293 (input) , Stau1-IP (GTX106566) , Post-IP lysate from control rabbit IgG-IP , Post-IP lysate from Stau1-IP

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.73 mg/mL
    Buffer
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    STAU1/Staufen (STAU1) (Staufen Double-Stranded RNA Binding Protein 1 (STAU1))
    Andere Bezeichnung
    Staufen (STAU1 Produkte)
    Synonyme
    STAU1 antikoerper, DKFZp459A0124 antikoerper, CG5753 antikoerper, Dmel\\CG5753 antikoerper, Dmstau antikoerper, STAU antikoerper, Stau antikoerper, Stauf antikoerper, dStau antikoerper, stau antikoerper, XStau antikoerper, XStau1 antikoerper, Staufen antikoerper, Staufen1 antikoerper, MGC145034 antikoerper, 5830401L18Rik antikoerper, AW549911 antikoerper, C85792 antikoerper, fi67e05 antikoerper, wu:fi67e05 antikoerper, zgc:77271 antikoerper, staufen double-stranded RNA binding protein 1 antikoerper, staufen antikoerper, RNA binding protein homolog antikoerper, staufen (RNA binding protein) homolog 1 (Drosophila) antikoerper, staufen double-stranded RNA binding protein 1 L homeolog antikoerper, STAU1 antikoerper, stau antikoerper, stau1 antikoerper, STAUFEN antikoerper, Stau1 antikoerper, stau1.L antikoerper
    Hintergrund
    Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5'UTR.

    Cellular Localization: Rough endoplasmic reticulum
    Molekulargewicht
    63 kDa
    Gen-ID
    6780
    Pathways
    Asymmetric Protein Localization
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