STAU1/Staufen Antikörper (AA 426-577)

Produktnummer ABIN1682917

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch STAU1/Staufen in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für STAU1/Staufen Antikörper (AA 426-577) (ABIN1682917)

Target: STAU1/Staufen (STAU1) (Staufen Double-Stranded RNA Binding Protein 1 (STAU1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STAU1/Staufen Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-STAU1/Staufen Antikörper

Bindungsspezifität: AA 426-577

Sequenz: QAVGVSQGHH TKDFTRAAPN PAKATVTAMI ARELLYGGTS PTAETILKNN ISSGHVPHGP LTRPSEQLDY LSRVQGFQVE YKDFPKNNKN EFVSLINCSS QPPLISHGIG KDVESCHDMA ALNILKLLSE LDQQSTEMPR TGNGPMSVCG RC

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 426-577 of human Staufen (NP_059347.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu STAU1/Staufen

Target: STAU1/Staufen (STAU1) (Staufen Double-Stranded RNA Binding Protein 1 (STAU1))

Andere Bezeichnung: STAU1

Hintergrund: Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5'UTR.,STAU1,PPP1R150,STAU,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microtubules,Neuroscience,STAU1

Molekulargewicht: 54 kDa/55 kDa/63 kDa

Gen-ID: 6780

UniProt: O95793

Pathways: Asymmetric Protein Localization