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ATG13 Antikörper (C-Term)

ATG13 Reaktivität: Human, Maus, Ratte WB, IF, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN783663
  • Target Alle ATG13 Antikörper anzeigen
    ATG13 (Autophagy Related 13 (ATG13))
    Bindungsspezifität
    • 15
    • 15
    • 10
    • 7
    • 7
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 65
    • 31
    • 30
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 81
    • 2
    Kaninchen
    Klonalität
    • 80
    • 3
    Polyklonal
    Konjugat
    • 26
    • 9
    • 8
    • 8
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ATG13 Antikörper ist unkonjugiert
    Applikation
    • 61
    • 38
    • 19
    • 13
    • 13
    • 13
    • 12
    • 9
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, mouse, rat
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    15 amino acid peptide near the carboxy terminus of human ATG13
    Top Product
    Discover our top product ATG13 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store the antibody (in aliquots) at -20 °C.
  • Target
    ATG13 (Autophagy Related 13 (ATG13))
    Andere Bezeichnung
    KIAA0652 (ATG13 Produkte)
    Synonyme
    zgc:63526 antikoerper, KIAA0652 antikoerper, PARATARG8 antikoerper, 1110053A20Rik antikoerper, D2Ertd391e antikoerper, Harbi1 antikoerper, Harbi1l antikoerper, RGD1310685 antikoerper, autophagy related 13 antikoerper, ATG13 autophagy related 13 homolog (S. cerevisiae) antikoerper, ATG13 antikoerper, atg13 antikoerper, Atg13 antikoerper
    Hintergrund
    Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein ATG1. ATG13 forms a complex with ULK1 and ULK2, the mammalian homologs of ATG1, and with FIP200. This complex is a target of TOR phosphorylation under normal conditions, inhibition of TOR by rapamycin or leucine deprivation leads to dephosphorylation of ATG13, ULK1 and ULK2, which then leads to autophagy. Knockdown of ATG13 inhibits autophagosome formation.Synonyms: UPF0630 protein KIAA0652
    Gen-ID
    9776
    NCBI Accession
    NP_001136145
    UniProt
    O75143
    Pathways
    PI3K-Akt Signalweg, Autophagie
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