IRF4 Antikörper (C-Term)
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- Target Alle IRF4 Antikörper anzeigen
- IRF4 (Interferon Regulatory Factor 4 (IRF4))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser IRF4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody detects IRF4 at C-term. IRF4 antibody is predicted to not cross-react with other IRF protein family members. IRF4 often migrates at a higher than predicted molecular weight in SDS-PAGE.
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human, mouse, rat
- Aufreinigung
- Affinity chromatography purified via peptide column
- Immunogen
- 16 amino acid peptide near the carboxy terminus of human IRF4
- Top Product
- Discover our top product IRF4 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS containing 0.02 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- Target
- IRF4 (Interferon Regulatory Factor 4 (IRF4))
- Andere Bezeichnung
- IRF4 (IRF4 Produkte)
- Synonyme
- LSIRF antikoerper, MUM1 antikoerper, NF-EM5 antikoerper, AI385587 antikoerper, IRF-4 antikoerper, Spip antikoerper, IRF4 antikoerper, si:ch73-170d1.2 antikoerper, irf4 antikoerper, interferon regulatory factor 4 antikoerper, interferon regulatory factor 4a antikoerper, Interferon regulatory factor 4 antikoerper, PWWP domain-containing protein MUM1 antikoerper, IRF4 antikoerper, Irf4 antikoerper, irf4a antikoerper, irf4 antikoerper, LOC612320 antikoerper, LOC100068881 antikoerper
- Hintergrund
- Interferons (IFNs) are involved in a multitude of immune interactions during viral infections and play a major role in both the induction and regulation of innate and adaptive antiviral mechanisms. During infection, host-virus interactions signal downstream molecules such as transcription factors such as IFN regulatory factor-3 (IRF3) which can act to stimulate transcription of IFN-a/b genes. Another member, IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. IRF4 expression is tightly regulated in resting primary T cells and plays an essential role in the homeostasis and function of mature lymphocytes. IRF4 is induced by Toll-like receptor (TLR) activation and acts as a negative regulator of TLR signaling.Synonyms: Interferon regulatory factor 4, LSIRF, Lymphocyte-specific interferon regulatory factor, MUM1, Multiple myeloma oncogene 1, NF-EM5
- Gen-ID
- 3662
- NCBI Accession
- NP_001182215
- UniProt
- Q15306
- Pathways
- Chromatin Binding
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