Glutamate Receptor 1 Antikörper (N-Term)

Produktnummer ABIN782441

Der Maus Monoklonal Anti-Glutamate Receptor 1-Antikörper wurde für WB validiert. Er ist geeignet, Glutamate Receptor 1 in Proben von Ratte und Maus zu detektieren.

Kurzübersicht für Glutamate Receptor 1 Antikörper (N-Term) (ABIN782441)

Target: Glutamate Receptor 1 (GLUR1)

Reaktivität: Ratte, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Glutamate Receptor 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RH95

Produktdetails anti-Glutamate Receptor 1 Antikörper

Bindungsspezifität: N-Term

Spezifität: Specific for the ~105k GluR1 protein.

Kreuzreaktivität (Details): Species reactivity (tested):Mouse and Rat.

Aufreinigung: Protein G Chromatography of Culture Supernatant

Immunogen: Peptide corresponding to amino acid residues from the N-terminal region of Rat GluR1.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody undiluted (in aliquots) at -20 °C.

Details zu Glutamate Receptor 1

Target: Glutamate Receptor 1 (GLUR1)

Andere Bezeichnung: Glutamate Receptor 1 / GLUR1

Hintergrund: The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by α-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain (Keinänen et al., 1990, Hollmann and Heinemann, 1994).Synonyms: AMPA-selective glutamate receptor 1, AMPA1, GLUH1, GRIA1, GluR-1, GluR-A, GluR-K1, Glutamate receptor ionotropic

Gen-ID: 50592

NCBI Accession: NP_113796

UniProt: P19490

Pathways: PI3K-Akt Signalweg