HIPK2 Antikörper
Kurzübersicht für HIPK2 Antikörper (ABIN781914)
Target
Alle HIPK2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- This antibody reacts to HIPK2.
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Kreuzreaktivität (Details)
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Species reactivity (expected):Rat.
Species reactivity (tested):Human. -
Aufreinigung
- Affinity chromatography on Protein A
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Immunogen
- HIPK2 antibody was raised against recombinant protein
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Isotyp
- IgG2a
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0,5 mg/mL
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Buffer
- PBS, pH 7.2
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- HIPK2 (Homeodomain Interacting Protein Kinase 2 (HIPK2))
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Andere Bezeichnung
- HIPK2
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Hintergrund
- HIPK2, a nuclear serine/threonine kinase similar to the MNB/DYRK type protein kinases, represses transcription mediated by homeodomain containing transcription factors. HIPK2 is activated by ultraviolet (UV) radiation and selectively phosphorylates p53 to promote p53-dependent gene expression. HIPK2 interacts with various proteins, including members of the p53 family, to regulate cell cycle and apoptosis. Variants of HIPK2 have been observed due to alternative splicing.Synonyms: Homeodomain-interacting protein kinase 2
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Gen-ID
- 28996
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NCBI Accession
- NP_001106710
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UniProt
- Q9H2X6
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Pathways
- Zellzyklus
Target
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