HCV NS5 Antikörper (AA 92-105)
Kurzübersicht für HCV NS5 Antikörper (AA 92-105) (ABIN781780)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 92-105
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Aufreinigung
- Protein G affinity chromatography
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Immunogen
- Recombinant Hepatitis C Virus nonstructural protein 5B (NS5B) RNA-dependent RNA polymerase (RdRp)
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Isotyp
- IgG1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- PBS pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Upon receipt, store (in aliquots) at -20 to -70 °C.
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: "Functional characterization of fingers subdomain-specific monoclonal antibodies inhibiting the hepatitis C virus RNA-dependent RNA polymerase." in: The Journal of biological chemistry, Vol. 283, Issue 35, pp. 24089-102, (2008) (PubMed).
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: "Functional characterization of fingers subdomain-specific monoclonal antibodies inhibiting the hepatitis C virus RNA-dependent RNA polymerase." in: The Journal of biological chemistry, Vol. 283, Issue 35, pp. 24089-102, (2008) (PubMed).
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- HCV NS5 (Hepatitis C Virus NS5 (HCV NS5))
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Andere Bezeichnung
- HCV NS5
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Substanzklasse
- Viral Protein
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Hintergrund
- Non-structural protein 5B (NS5B) represents the RNA-dependent RNA polymerase (RdRp) of Hepatitis C Virus, which is a small positive strand RNA virus in the family Flaviviridae. HCV is a major causative agent of acute and chronic hepatitis, hepatocellular carcinoma and liver cirrhosis. The single subunit RNA-dependent RNA polymerase is absolutely essential for the viral replication.Synonyms: Hepatitis C Virus, RNA-directed RNA polymerase NS5B
Target
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