HCV NS5 Antikörper (AA 2190-2300)
Kurzübersicht für HCV NS5 Antikörper (AA 2190-2300) (ABIN111768)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 2190-2300
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Aufreinigung
- Protein G Chromatography.
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Immunogen
- Recombinant antigen (HCV) genotype 1b. Remarks:
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Isotyp
- IgG1
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Applikationshinweise
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Suitable for use in ELISA (approx. 10e-6), Western Blot (1/1000) and Immunohistochemistry(Cryostat liver sections: 1/20).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- PBS, pH 7.2 containing 0.01 % Sodium Azide as preservative.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Do not freeze working dilutions
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- HCV NS5 (Hepatitis C Virus NS5 (HCV NS5))
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Andere Bezeichnung
- HCV NS5
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Substanzklasse
- Viral Protein
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Hintergrund
- HCV is classified into the genus Hepacivirus of the family Flaviviridae. Like all the members of the family, HCV is an enveloped, single-stranded, positive-sense RNA virus. Its genome (about 9600 nt) is flanked at both termini by conserved, highly structured non-translated regions (NTRs) and encodes a polyprotein precursor (about 3000 aa), which is proteolytically processed by host and viral proteases to produce the structural (core, E1, E2 and p7) and non-structural (NS2, NS3, NS4A, NS4B, NS5A and NS5B) proteins of the virus. Recently, an additional protein has been identified, whose function remains unknown. NS5A is a ~56 kDa pleiotropic protein with key roles in both viral RNA replication and modulation of the physiology of the host cellSynonyms: Hepatitis C Virus Non-structural protein NS5A
Target
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