HCV NS5 Antikörper (AA 2190-2300)

Produktnummer ABIN111768

Produktdetails anti-HCV NS5 Antikörper

Target: HCV NS5 (Hepatitis C Virus NS5 (HCV NS5))

Bindungsspezifität: AA 2190-2300

Reaktivität: Hepatitis C Virus (HCV)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HCV NS5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Aufreinigung: Protein G Chromatography.

Immunogen: Recombinant antigen (HCV) genotype 1b. Remarks:

Klon: 7-D4

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Suitable for use in ELISA (approx. 10e-6), Western Blot (1/1000) and Immunohistochemistry(Cryostat liver sections: 1/20).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.2 containing 0.01 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Do not freeze working dilutions

Details zu HCV NS5

Target: HCV NS5 (Hepatitis C Virus NS5 (HCV NS5))

Andere Bezeichnung: HCV NS5 (HCV NS5 Produkte)

Substanzklasse: Viral Protein

Hintergrund: HCV is classified into the genus Hepacivirus of the family Flaviviridae. Like all the members of the family, HCV is an enveloped, single-stranded, positive-sense RNA virus. Its genome (about 9600 nt) is flanked at both termini by conserved, highly structured non-translated regions (NTRs) and encodes a polyprotein precursor (about 3000 aa), which is proteolytically processed by host and viral proteases to produce the structural (core, E1, E2 and p7) and non-structural (NS2, NS3, NS4A, NS4B, NS5A and NS5B) proteins of the virus. Recently, an additional protein has been identified, whose function remains unknown. NS5A is a ~56 kDa pleiotropic protein with key roles in both viral RNA replication and modulation of the physiology of the host cellSynonyms: Hepatitis C Virus Non-structural protein NS5A