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HCV NS5 Antikörper (AA 92-105)

HCV NS5 Reaktivität: Human WB, EIA, IP Wirt: Maus Monoclonal 7G8 unconjugated
Produktnummer ABIN781782
  • Target Alle HCV NS5 Produkte
    HCV NS5 (Hepatitis C Virus NS5 (HCV NS5))
    Bindungsspezifität
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 92-105
    Reaktivität
    • 7
    • 3
    Human
    Wirt
    • 9
    • 1
    Maus
    Klonalität
    • 9
    • 1
    Monoklonal
    Konjugat
    • 10
    Dieser HCV NS5 Antikörper ist unkonjugiert
    Applikation
    • 9
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA), Immunoprecipitation (IP)
    Aufreinigung
    Protein G affinity chromatography
    Immunogen
    Recombinant Hepatitis C Virus nonstructural protein 5B (NS5B) RNA-dependent RNA polymerase (RdRp)
    Klon
    7G8
    Isotyp
    IgG1
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS pH 7.4, with 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Upon receipt, store (in aliquots) at -20 to -70 °C.
  • Nikonov, Juronen, Ustav: "Functional characterization of fingers subdomain-specific monoclonal antibodies inhibiting the hepatitis C virus RNA-dependent RNA polymerase." in: The Journal of biological chemistry, Vol. 283, Issue 35, pp. 24089-102, (2008) (PubMed).

  • Target
    HCV NS5 (Hepatitis C Virus NS5 (HCV NS5))
    Andere Bezeichnung
    HCV NS5 (HCV NS5 Produkte)
    Substanzklasse
    Viral Protein
    Hintergrund
    Non-structural protein 5B (NS5B) represents the RNA-dependent RNA polymerase (RdRp) of Hepatitis C Virus, which is a small positive strand RNA virus in the family Flaviviridae. HCV is a major causative agent of acute and chronic hepatitis, hepatocellular carcinoma and liver cirrhosis. The single subunit RNA-dependent RNA polymerase is absolutely essential for the viral replication.Synonyms: Hepatitis C Virus, RNA-directed RNA polymerase NS5B
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