CD3 Antikörper

Produktnummer ABIN781714

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD3 in FACS und IHC (fro). Er zeigt eine Reaktivität gegenüber Human und Rhesusaffen.

Kurzübersicht für CD3 Antikörper (ABIN781714)

Target: CD3

Reaktivität: Human, Rhesusaffen

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD3 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: CRIS-7

Produktdetails anti-CD3 Antikörper

Spezifität: This antibody detects Human CD3. Antigen Distribution on Isolated cells: Peripheral T cells.

Kreuzreaktivität (Details): Species reactivity (tested):Human, Rhesus Monkey.

Aufreinigung: Affinity Chromatography

Immunogen: Stimulated Human leukocytes

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore by adding 0.5 mL distilled water

Buffer: Stock solution contains 0.2 mg/mL IgG, PBS, pH 7.2 with 5 mg/mL BSA as stabilizer and 0.09 % Sodium Azide as a preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CD3

Target: CD3

Andere Bezeichnung: CD3

Hintergrund: The CD3 antigen is a protein complex composed of four distinct chains (CD3γ, CD3δ and two CD3ε) that associate with the T cell receptor (TCR) and the ζ-chain to generate an activation signal in T lymphocytes. The TCR, ζ-chain and CD3 Molecules together comprise the TCR complex. The CD3γ, CD3δ and CD3ε chains are highly related cell surface proteins of the immunoglobulin superfamily containing a single extracellular immunoglobulin domain.Synonyms: T-cell surface antigen T3/Leu-4, T-cell surface glycoprotein CD3, T3/Leu-4

Gen-ID: 916

NCBI Accession: NP_000724

UniProt: P07766

Pathways: T-Zell Rezeptor Signalweg, Ubiquitin Proteasome Pathway