CD3 Antikörper
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- Target Alle CD3 Antikörper anzeigen
- CD3
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Reaktivität
- Human, Rhesusaffen
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD3 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Spezifität
- This antibody detects Human CD3. Antigen Distribution on Isolated cells: Peripheral T cells.
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human, Rhesus Monkey.
- Aufreinigung
- Affinity Chromatography
- Immunogen
- Stimulated Human leukocytes
- Klon
- CRIS-7
- Isotyp
- IgG2a
- Top Product
- Discover our top product CD3 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Rekonstitution
- Restore by adding 0.5 mL distilled water
- Buffer
- Stock solution contains 0.2 mg/mL IgG, PBS, pH 7.2 with 5 mg/mL BSA as stabilizer and 0.09 % Sodium Azide as a preservative
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- CD3
- Andere Bezeichnung
- CD3 (CD3 Produkte)
- Hintergrund
- The CD3 antigen is a protein complex composed of four distinct chains (CD3γ, CD3δ and two CD3ε) that associate with the T cell receptor (TCR) and the ζ-chain to generate an activation signal in T lymphocytes. The TCR, ζ-chain and CD3 Molecules together comprise the TCR complex. The CD3γ, CD3δ and CD3ε chains are highly related cell surface proteins of the immunoglobulin superfamily containing a single extracellular immunoglobulin domain.Synonyms: T-cell surface antigen T3/Leu-4, T-cell surface glycoprotein CD3, T3/Leu-4
- Gen-ID
- 916
- NCBI Accession
- NP_000724
- UniProt
- P07766
- Pathways
- T-Zell Rezeptor Signalweg, Ubiquitin Proteasome Pathway
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