CD3 Antikörper

Produktnummer ABIN7073386

Produktdetails anti-CD3 Antikörper

Target: CD3

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD3 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blotting (WB)

Kreuzreaktivität: Human, Ratte

Aufreinigung: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse CD3

Anwendungsinformationen

Applikationshinweise: WB (H,M,R) 1:500-1:1000, IHC/IF (H,M,R) 1:250-1:1000/1:250-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Referenzen für anti-CD3 Antikörper (ABIN7073386)

Feng, Yang, Luo, Sun, Lv, Wan, Guan, Xiao, Liu, Li, Dong, Yang: "The kinase PDK1 regulates regulatory T cell survival via controlling redox homeostasis." in: Theranostics, Vol. 11, Issue 19, pp. 9503-9518, (2022) (PubMed).

He, Wang, Lu, Yang, Xue, Zhu, Zhang, Fan: "Single-cell RNA sequencing reveals heterogeneous tumor and immune cell populations in early-stage lung adenocarcinomas harboring EGFR mutations." in: Oncogene, Vol. 40, Issue 2, pp. 355-368, (2021) (PubMed).

Chen, Gu, Jia, Liu, Liu, Liu, Xu, Lin, Lin, Liu, Chen, Xu, Yuan, Zhang, Zhang, Xiao, Gu: "Optimization Strategy for Generating Gene-edited Tibet Minipigs by Synchronized Oestrus and Cytoplasmic Microinjection." in: International journal of biological sciences, Vol. 15, Issue 12, pp. 2719-2732, (2020) (PubMed).

Details zu CD3

Target: CD3

Andere Bezeichnung: CD3 (CD3 Produkte)

Synonyme: CD3 antikoerper, AI504783 antikoerper, CD3epsilon antikoerper, T3e antikoerper, cd3-gamma antikoerper, cd3g antikoerper, cd3g-a antikoerper, cd3g/d antikoerper, cd3gd antikoerper, t3g antikoerper, CD3e molecule antikoerper, CD3d molecule antikoerper, CD3 antigen, epsilon polypeptide antikoerper, CD3g molecule S homeolog antikoerper, CD3E antikoerper, CD3D antikoerper, Cd3e antikoerper, cd3g.S antikoerper

Hintergrund: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development.

Molekulargewicht: 21 kDa

Gen-ID: 12501

NCBI Accession: NP_031674

UniProt: P22646

Pathways: T-Zell Rezeptor Signalweg, Ubiquitin Proteasome Pathway