MAP2 Antikörper
Kurzübersicht für MAP2 Antikörper (ABIN781313)
Target
Alle MAP2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- Cytoplasm
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Aufreinigung
- Protein G-Sepharose affinity purified.
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Immunogen
- Recombinant fragment of Human MAP2 (C-terminus).
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 50µg/50µl
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Buffer
- 0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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- MAP2 (Microtubule-Associated Protein 2 (MAP2))
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Andere Bezeichnung
- MAP2
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Hintergrund
- Microtubule-associated protein 2 (MAP2) is a neuronal phosphoprotein that regulates the structure and stability of microtubules, neuronal morphogenesis, cytoskeleton dynamics and organelle trafficking in axons and dendrites. Phosphorylation of MAP2 modulates its association with the cytoskeleton and is developmentally regulated. Serine 136, threonine 1620 and threonine 1623 of MAP2 are phosphorylated by GSK3 and p44/42 MAP kinases. Phosphorylation at threonine 1620/1623 by GSK3 inhibits MAP2 association with microtubules and microtubule stability.
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Molekulargewicht
- 50kDa
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NCBI Accession
- NM_031846
Target
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