Topoisomerase II alpha Antikörper (AA 1400-1531)

Produktnummer ABIN8125246

Der Maus Monoklonal anti-Topoisomerase II alpha Antikörper (Klon AB1403) (ABIN8125246) detektiert spezifisch Topoisomerase II alpha in IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für Topoisomerase II alpha Antikörper (AA 1400-1531) (ABIN8125246)

Target: Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Topoisomerase II alpha Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: AB1403

Produktdetails anti-Topoisomerase II alpha Antikörper

Bindungsspezifität: AA 1400-1531

Verwendungszweck: Topoisomerase IIα Mouse mAb (Ready to Use)

Spezifität: The antibody can specifically recognize human Topoisomerase IIα protein.

Aufreinigung: The antibody was purified by protein G affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 1400 - 1531 of the human Topoisomerase IIalpha protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: It has been optimized for direct use, requiring no further dilution.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze

Lagerung: 4 °C

Informationen zur Lagerung: Store at 4°C. Avoid freeze.

Details zu Topoisomerase II alpha

Target: Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))

Andere Bezeichnung: Topoisomerase IIalpha

Hintergrund:

Synonyms: alpha isozyme, ATP hydrolyzing DNA topoisomerase II alfa, DNA gyrase, DNA topoisomerase (ATP hydrolyzing) , DNA topoisomerase 2 alpha, DNA topoisomerase 2-alpha, DNA topoisomerase II 170 kD, DNA topoisomerase II alpha isozyme, DNA topoisomerase II, DNA Topoisomerase2, TOP 2A, TOP2, TOP2A, TOP2A_HUMAN, Topoisomerase DNA II alpha 170 kDa, TP2A

Background: Topoisomerase IIα (Topo IIα) is a nuclear protein with a molecular weight of 170 kDa. It belongs to the topoisomerase family and is expressed in proliferating cells. The main function is to maintain the spatial conformation of DNA and ensure its function. It is mainly used for the study of drug resistance.

Gene Name: TOP2A

Protein Name: Topoisomerase IIα

Gen-ID: 7153

UniProt: P11388

Pathways: Zellzyklus, Mitotic G1-G1/S Phases