TLR3 Antikörper (pTyr759)

Produktnummer ABIN8125237

Der Kaninchen Polyklonal anti-TLR3 Antikörper (ABIN8125237) detektiert spezifisch TLR3 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für TLR3 Antikörper (pTyr759) (ABIN8125237)

Target: TLR3 (Toll-Like Receptor 3 (TLR3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLR3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TLR3 Antikörper

Bindungsspezifität: pTyr759

Verwendungszweck: TLR3 (Phospho Tyr759) Antibody

Spezifität: This antibody detects endogenous levels of TLR3 (Phospho-Tyr759) at Human, Mouse,Rat

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human TLR3 (Phospho-Tyr759)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu TLR3

Target: TLR3 (Toll-Like Receptor 3 (TLR3))

Andere Bezeichnung: TLR3

Hintergrund:

Synonyms: Toll-like receptor 3 (CD antigen CD283)

Background: The protein encoded byThis gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses. Use of alternative polyadenylation sites to generate

Gene Name: TLR3

Protein Name: TLR3 (Phospho-Tyr759)

Gen-ID: 7098

UniProt: O15455

Pathways: TLR Signalweg, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades