Thyroperoxidase Antikörper (AA 600-700)

Produktnummer ABIN8125211

Dieser Maus Monoklonal Antikörper detektiert spezifisch Thyroperoxidase in WB, IHC, ELISA und IF. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Thyroperoxidase Antikörper (AA 600-700) (ABIN8125211)

Target: Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Thyroperoxidase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Klon: AB1601

Produktdetails anti-Thyroperoxidase Antikörper

Bindungsspezifität: AA 600-700

Verwendungszweck: Thyroid Peroxidase (TPO) mouse mAb

Spezifität: This antibody detects endogenous levels of TPO protein.

Aufreinigung: The antibody was purified by protein G affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 600 - 700 of the human Thyroid Peroxidase protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC, 1:200-1:1000 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at-20°C. Avoid freeze / thaw cycles.

Details zu Thyroperoxidase

Target: Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))

Andere Bezeichnung: Thyroid Peroxidase

Hintergrund:

Synonyms: Thyroid peroxidase,TPO,

Background: This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011]

Gene Name: TPO

Protein Name: Thyroid Peroxidase (TPO)

Gen-ID: 3662

UniProt: P07202

Pathways: Thyroid Hormone Synthesis