Thyroperoxidase Antikörper

Produktnummer ABIN7270865

Der Kaninchen Monoklonal anti-Thyroperoxidase Antikörper wird verwendet zum Nachweis von Thyroperoxidase in Proben von Human. Er wurde validiert für IHC.

Kurzübersicht für Thyroperoxidase Antikörper (ABIN7270865)

Target: Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Thyroperoxidase Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-Thyroperoxidase Antikörper

Verwendungszweck: Thyroid Peroxidase Rabbit mAb

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human Thyroid Peroxidase

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Thyroperoxidase

Target: Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))

Andere Bezeichnung: TPO

Substanzklasse: Viral Protein

Hintergrund: This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011],MSA, TDH2A, TPX,Cancer,Cell Biology & Developmental Biology,Endocrine & Metabolism,Growth factors,Neuroscience,Signal Transduction,TPO

Molekulargewicht: 103kDa

Gen-ID: 7173

UniProt: P07202

Pathways: Thyroid Hormone Synthesis