TCL1A Antikörper (AA 50-114)
Kurzübersicht für TCL1A Antikörper (AA 50-114) (ABIN8125091)
Target
Alle TCL1A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 50-114
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Verwendungszweck
- TCL1 mouse mAb
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Spezifität
- The antibody can specifically recognize human TCL1 protein.
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Aufreinigung
- The antibody was purified by affinity chromatography using a specific immunogen.
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Immunogen
- A synthetic peptide corresponding to the amino acid region 50 - 114 of the human TCL1 protein.
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Isotyp
- IgG
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Applikationshinweise
- IHC, 1:200-1:400
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid freeze / thaw cycles
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at-20°C. Avoid freeze / thaw cycles.
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- TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))
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Andere Bezeichnung
- TCL1
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Hintergrund
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Synonyms: Anti TCL1A, Lymphoma/leukemia, T-cell, Oncogene TCL-1, Oncogene TCL1, P14 TCL1, P14 TCL1 protein, Protein p14 TCL1, T cell leukemia 1, T cell lymphoma 1, T cell lymphoma 1A, T-cell leukemia/lymphoma 1A, T-cell leukemia/lymphoma protein 1A, TCL 1 protein, TCL1, TCL1 oncogene, TCL1 PEN, Tcl1a, TCL1A, TCL1A_HUMAN
Background: TCL1 belongs to the proto oncogene family. It promotes the nuclear translocation of AKT1 by activating the phosphorylation of AKT1, AKT2 and Akt3, so as to promote cell proliferation and survival and stabilize mitochondrial membrane potential. The encoded protein is involved in embryonic development, T cell carcinogenesis, pre lymphocyte carcinogenesis and B cell carcinogenesis.
Gene Name: TCL1A
Protein Name: TCL1
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Gen-ID
- 8115
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UniProt
- P56279
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Pathways
- Stem Cell Maintenance
Target
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