TCL1A Antikörper (AA 32-66)
Kurzübersicht für TCL1A Antikörper (AA 32-66) (ABIN1944776)
Target
Alle TCL1A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 32-66
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Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This TCL1A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 32-66 amino acids from the Central region of human TCL1A.
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Isotyp
- Ig Fraction
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Applikationshinweise
- WB: 1:1000. FC: 1:25
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Haltbarkeit
- 6 months
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: "The protooncogene TCL1 is an Akt kinase coactivator." in: Molecular cell, Vol. 6, Issue 2, pp. 395-407, (2000) (PubMed).
: "Identification of the TCL1 gene involved in T-cell malignancies." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 26, pp. 12530-4, (1995) (PubMed).
: "Characterization and localization of the TCL-1 oncogene product." in: Cancer research, Vol. 54, Issue 24, pp. 6297-301, (1995) (PubMed).
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- TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))
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Andere Bezeichnung
- TCL1A
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Hintergrund
- Enhances the phosphorylation and activation of AKT1, AKT2 and AKT3. Promotes nuclear translocation of AKT1. Enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival.
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Molekulargewicht
- 13460
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Gen-ID
- 8115
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UniProt
- P56279
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Pathways
- Stem Cell Maintenance
Target
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