TCL1A Antikörper (AA 10-104)

Produktnummer ABIN5542543

Produktdetails anti-TCL1A Antikörper

Target: TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))

Bindungsspezifität: AA 10-104

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TCL1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human TCL1A (AA: 10-104) expressed in E. coli.

Klon: 2E3A5

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Details zu TCL1A

Target: TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))

Andere Bezeichnung: TCL1A (TCL1A Produkte)

Synonyme: TCL1A antikoerper, Tcl1a antikoerper, TCL1 antikoerper, Tcl1 antikoerper, T-cell leukemia/lymphoma 1A antikoerper, T cell lymphoma breakpoint 1 antikoerper, TCL1A antikoerper, Tcl1 antikoerper, Tcl1a antikoerper

Hintergrund:

Description: Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998 [PubMed 9520462]). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730) (Laine et al., 2000 [PubMed 10983986]).

Aliases: TCL1

Molekulargewicht: 13.5 kDa

Gen-ID: 8115

HGNC: 8115

Pathways: Stem Cell Maintenance