TCL1A Antikörper (AA 50-114)

Produktnummer ABIN8125088

Dieser Maus Monoklonal Antikörper detektiert spezifisch TCL1A in IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für TCL1A Antikörper (AA 50-114) (ABIN8125088)

Target: TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TCL1A Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: AB1425

Produktdetails anti-TCL1A Antikörper

Bindungsspezifität: AA 50-114

Verwendungszweck: TCL1 Mouse mAb (Ready to Use)

Spezifität: The antibody can specifically recognize human TCL1 protein.

Aufreinigung: The antibody was purified by protein G affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 50 - 114 of the human TCL1 protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: It has been optimized for direct use, requiring no further dilution.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze

Lagerung: 4 °C

Informationen zur Lagerung: Store at 4°C. Avoid freeze.

Details zu TCL1A

Target: TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))

Andere Bezeichnung: TCL1

Hintergrund:

Synonyms: Anti TCL1A, Lymphoma/leukemia, T-cell, Oncogene TCL-1, Oncogene TCL1, P14 TCL1, P14 TCL1 protein, Protein p14 TCL1, T cell leukemia 1, T cell lymphoma 1, T cell lymphoma 1A, T-cell leukemia/lymphoma 1A, T-cell leukemia/lymphoma protein 1A, TCL 1 protein, TCL1, TCL1 oncogene, TCL1 PEN, Tcl1a, TCL1A, TCL1A_HUMAN

Background: TCL1 belongs to the proto oncogene family. It promotes the nuclear translocation of AKT1 by activating the phosphorylation of AKT1, AKT2 and Akt3, so as to promote cell proliferation and survival and stabilize mitochondrial membrane potential. The encoded protein is involved in embryonic development, T cell carcinogenesis, pre lymphocyte carcinogenesis and B cell carcinogenesis.

Gene Name: TCL1A

Protein Name: TCL1

Gen-ID: 8115

UniProt: P56279

Pathways: Stem Cell Maintenance