SPHK1 Antikörper (pSer225)

Produktnummer ABIN8124895

Der Kaninchen Polyklonal anti-SPHK1 Antikörper (ABIN8124895) detektiert spezifisch SPHK1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für SPHK1 Antikörper (pSer225) (ABIN8124895)

Target: SPHK1 (Sphingosine Kinase 1 (SPHK1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPHK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SPHK1 Antikörper

Bindungsspezifität: pSer225

Verwendungszweck: SPHK1 (Phospho Ser225) Antibody

Spezifität: This antibody detects endogenous levels of SPHK1 (Phospho-Ser225) at Human, Mouse,Rat

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human SPHK1 (Phospho-Ser225)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu SPHK1

Target: SPHK1 (Sphingosine Kinase 1 (SPHK1))

Andere Bezeichnung: SPHK1

Hintergrund:

Synonyms: Sphingosine kinase 1 (SK 1) (SPK 1) (EC 2.7.1.91)

Background: The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],

Gene Name: SPHK1 SPHK SPK

Protein Name: SPHK1 (Phospho-Ser225)

Gen-ID: 8877

UniProt: Q9NYA1

Pathways: VEGF Signaling