SPHK1 Antikörper (AA 160-240)
Kurzübersicht für SPHK1 Antikörper (AA 160-240) (ABIN8124894)
Target
Alle SPHK1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 160-240
-
Verwendungszweck
- SPHK1 Antibody
-
Spezifität
- SPHK1 Polyclonal Antibody detects endogenous levels of protein.
-
Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
Immunogen
- Synthesized peptide derived from human protein . at AA range: 160-240
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB 1:500-2000 ELISA 1:5000-20000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C/1 year
-
Haltbarkeit
- 12 months
-
-
- SPHK1 (Sphingosine Kinase 1 (SPHK1))
-
Andere Bezeichnung
- SPHK1
-
Hintergrund
-
Background: The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],
Gene Name: SPHK1 SPHK SPK
Protein Name: Sphingosine kinase 1 (SK 1) (SPK 1) (EC 2.7.1.91)
-
Gen-ID
- 8877
-
UniProt
- Q9NYA1
-
Pathways
- VEGF Signaling
Target
-