PSMA7 Antikörper (AA 168-218)
Kurzübersicht für PSMA7 Antikörper (AA 168-218) (ABIN8124043)
Target
Alle PSMA7 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 168-218
-
Verwendungszweck
- PSA7 Antibody
-
Spezifität
- This antibody detects endogenous levels of PSA7 at Human/Mouse/Rat
-
Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
Immunogen
- Synthesized peptide derived from human PSA7 AA range: 168-218
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB 1:500-2000,IHC 1:50-300
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C/1 year
-
Haltbarkeit
- 12 months
-
-
- PSMA7 (Proteasome Subunit alpha 7 (PSMA7))
-
Andere Bezeichnung
- PSA7
-
Hintergrund
-
Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway.This gene encodes a member of the peptidase T1A family that functions as a 20S core alpha subunit. The encoded protein interacts with the hepatitis B virus X protein and plays a role in regulating hepatitis C virus internal ribosome entry site (IRES) activity, an activity essential for viral replication. The encoded protein also plays a role in the cellular stress response by regulating hypoxia-inducible factor-1alpha. A pseudogene of this gene is located on the long arm of chromosome 9. [provided by RefSeq, Jul 2012],
Gene Name: PSMA7 HSPC
Protein Name: PSA7
-
Gen-ID
- 5688
-
UniProt
- O14818
-
Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
Target
-