Perforin 1 Antikörper (AA 1-100)

Produktnummer ABIN8123650

Der Maus Monoklonal anti-Perforin 1 Antikörper (Klon AB1420) (ABIN8123650) detektiert spezifisch Perforin 1 in WB, IHC, ELISA und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Perforin 1 Antikörper (AA 1-100) (ABIN8123650)

Target: Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Perforin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Klon: AB1420

Produktdetails anti-Perforin 1 Antikörper

Bindungsspezifität: AA 1-100

Verwendungszweck: Perforin mouse mAb

Spezifität: The antibody can specifically recognize human Perforin protein.

Aufreinigung: The antibody was purified by protein G affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 1 - 100 of the human Perforin protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC, 1:100-1:500 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at-20°C. Avoid freeze / thaw cycles.

Details zu Perforin 1

Target: Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))

Andere Bezeichnung: Perforin

Hintergrund:

Synonyms: Cytolysin, FLH2, HPLH2, Lymphocyte pore-forming protein, P1, PERF_HUMAN, perforin 1 (pore forming protein) , Perforin 1, Perforin-1, PFP, PGFL, PIGF, PIGF-2, PLGF, Pore forming protein, prf1, SHGC-10760

Background: Perforin is a specific marker of activated cytotoxic T cells and natural killer cells. It can destroy the corresponding target cell membrane and induce apoptosis. It is mainly expressed in CD3 negative and CD56 positive NK cells, CD3 positive large granular lymphocytes and γδ Type T cells. It is mainly used for the auxiliary diagnosis of NK cell lymphoma and NK cell like T-cell lymphoma.

Gene Name: PRF1 PFP

Protein Name: Perforin

Gen-ID: 5551

UniProt: P14222

Pathways: Apoptose, Caspase Kaskade in der Apoptose