KISS1 Antikörper

Produktnummer ABIN8122567

Der Kaninchen Polyklonal anti-KISS1 Antikörper (ABIN8122567) detektiert spezifisch KISS1 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für KISS1 Antikörper (ABIN8122567)

Target: KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KISS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-KISS1 Antikörper

Verwendungszweck: KISS1 Antibody

Spezifität: KISS1 Polyclonal Antibody detects endogenous levels of protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000 ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu KISS1

Target: KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))

Andere Bezeichnung: KISS1

Hintergrund:

Background: This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may inhibit chemotaxis and invasion and thereby attenuate metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A protein product of this gene, kisspeptin, stimulates gonadotropin-releasing hormone (GnRH)-induced gonadotropin secretion and regulates the pubertal activation of GnRH nuerons. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third position in a stop codon. When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues. [provided by R

Gene Name: KISS1 PP5098

Protein Name: Metastasis-suppressor KiSS-1 (Kisspeptin-1) [Cleaved into: Metastin (Kisspeptin-54)Kisspeptin-14Kisspeptin-13Kisspeptin-10]

Gen-ID: 3814

UniProt: Q15726

Pathways: Positive Regulation of Peptide Hormone Secretion