FGFR3 Antikörper (pTyr724)

Produktnummer ABIN8121444

Der Kaninchen Polyklonal anti-FGFR3 Antikörper wird verwendet zum Nachweis von FGFR3 in Proben von Human, Maus und Ratte. Er wurde validiert für WB.

Kurzübersicht für FGFR3 Antikörper (pTyr724) (ABIN8121444)

Target: FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FGFR3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FGFR3 Antikörper

Bindungsspezifität: pTyr724

Verwendungszweck: FGFR3 (Phospho Tyr724) Antibody

Spezifität: This antibody detects endogenous levels of FGFR3 (Phospho-Tyr724) at Human, Mouse,Rat

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human FGFR3 (Phospho-Tyr724)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu FGFR3

Target: FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))

Andere Bezeichnung: FGFR3

Hintergrund:

Synonyms: Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)

Background: This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dys

Gene Name: FGFR3 JTK4

Protein Name: FGFR3 (Phospho-Tyr724)

Gen-ID: 2261

UniProt: P22607

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance, Growth Factor Binding