EPAS1 Antikörper (Lys385)
Kurzübersicht für EPAS1 Antikörper (Lys385) (ABIN8121183)
Target
Alle EPAS1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Lys385
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Verwendungszweck
- EPAS-1 Antibody
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Spezifität
- EPAS-1 Polyclonal Antibody detects endogenous levels of EPAS-1 protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Synthesized peptide derived from human EPAS-1 around the non-acetylation site of K385.
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Isotyp
- IgG
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Applikationshinweise
- IF 1:50-200 WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000. Not yet tested in other applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))
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Andere Bezeichnung
- EPAS-1
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Hintergrund
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Synonyms: EPAS1, BHLHE73, HIF2A, MOP2, PASD2, Endothelial PAS domain-containing protein 1, EPAS-1, Basic-helix-loop-helix-PAS protein MOP2, Class E basic helix-loop-helix protein 73, bHLHe73, HIF-1-alpha-like factor, HLF, Hypoxia-inducible factor 2-alpha, HIF-2-alpha, HIF2-alpha, Member of PAS protein 2, PAS domain-containing protein 2
Background: endothelial PAS domain protein 1(EPAS1) Homo sapiens This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4. [provided by RefSeq, Nov 2009],
Gene Name: EPAS1 BHLHE73 HIF2A MOP2 PASD2
Protein Name: Endothelial PAS domain-containing protein 1
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Gen-ID
- 2034
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UniProt
- Q99814
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Pathways
- Signaling Events mediated by VEGFR1 and VEGFR2, Warburg Effekt
Target
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