Dystrophin Antikörper

Produktnummer ABIN8121097

Der Kaninchen Monoklonal anti-Dystrophin Antikörper (Klon AB2266) (ABIN8121097) detektiert spezifisch Dystrophin in IHC, WB, ELISA, IP und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für Dystrophin Antikörper (ABIN8121097)

Target: Dystrophin (DMD)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Dystrophin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

Klon: AB2266

Produktdetails anti-Dystrophin Antikörper

Verwendungszweck: Dystrophin Rabbit mAb

Spezifität: This antibody detects endogenous levels of Dystrophin protein.

Aufreinigung: The antibody was purified by protein A affinity chromatography.

Immunogen: Recombinant protein (or fragment).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB, 1:500-1:2000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at-20°C. Avoid freeze / thaw cycles.

Details zu Dystrophin

Target: Dystrophin (DMD)

Andere Bezeichnung: Dystrophin

Hintergrund:

Synonyms: Dystrophin

Background: This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC) , which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD) , Becker muscular dystrophy (BMD) , or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene. [provided by RefSeq, Dec 2016]

Gene Name: DMD

Protein Name: Dystrophin

Gen-ID: 1756

UniProt: P11532

Pathways: Skeletal Muscle Fiber Development