DUSP6 Antikörper (pSer197)

Produktnummer ABIN8121074

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch DUSP6 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für DUSP6 Antikörper (pSer197) (ABIN8121074)

Target: DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DUSP6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DUSP6 Antikörper

Bindungsspezifität: pSer197

Verwendungszweck: MKP-3 (Phospho Ser197) Antibody

Spezifität: This antibody detects endogenous levels of MKP-3 (Phospho-Ser197) at Human, Mouse,Rat

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human MKP-3 (Phospho-Ser197)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu DUSP6

Target: DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))

Andere Bezeichnung: MKP-3

Hintergrund:

Synonyms: Dual specificity protein phosphatase 6 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase PYST1) (Mitogen-activated protein kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3)

Background: The protein encoded byThis gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Mutations in t

Gene Name: DUSP6 MKP3 PYST1

Protein Name: MKP-3 (Phospho-Ser197)

Gen-ID: 1848

UniProt: Q16828

Pathways: Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades