CD2AP Antikörper (AA 320-400)

Produktnummer ABIN8120330

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CD2AP in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für CD2AP Antikörper (AA 320-400) (ABIN8120330)

Target: CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD2AP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-CD2AP Antikörper

Bindungsspezifität: AA 320-400

Verwendungszweck: CD2AP Antibody

Spezifität: CD2AP Polyclonal Antibody detects endogenous levels of protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human protein . at AA range: 320-400

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000 ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu CD2AP

Target: CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))

Andere Bezeichnung: CD2AP

Hintergrund:

Background: This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease. [provided by RefSeq, Jul 2008],

Gene Name: CD2AP

Protein Name: CD2-associated protein (Adapter protein CMS) (Cas ligand with multiple SH3 domains)

Gen-ID: 23607

UniProt: Q9Y5K6