CD2AP Antikörper (AA 689-639)

Produktnummer ABIN7450093

Produktdetails anti-CD2AP Antikörper

Target: CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))

Bindungsspezifität: AA 689-639

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD2AP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Verwendungszweck: Rabbit anti-CD2AP Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: Between AA 689 and 639

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu CD2AP

Target: CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))

Andere Bezeichnung: CD2AP (Cd2ap Produkte)

Synonyme: cd2apl antikoerper, fj51c01 antikoerper, im:7153970 antikoerper, si:ch211-207n9.1 antikoerper, wu:fj51c01 antikoerper, zgc:103705 antikoerper, DKFZp469E061 antikoerper, CMS antikoerper, AL024079 antikoerper, C78928 antikoerper, METS-1 antikoerper, Mets1 antikoerper, CD2-associated protein L homeolog antikoerper, CD2 associated protein antikoerper, CD2-associated protein antikoerper, cd2ap.L antikoerper, CD2AP antikoerper, cd2ap antikoerper, Cd2ap antikoerper

Hintergrund: Background: CD2-associated protein (CD2AP) seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. In collaboration with CBLC, it modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. It also controls CBLC function, converting it from an inhibitor to a promoter of RET degradation. CD2AP may play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell and may anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. CD2AP is also required for cytokinesis [taken from the Universal Protein Resource (UniProt) Q9Y5K6].

Gen-ID: 23607

NCBI Accession: NP_036252

UniProt: Q9Y5K6