CD2AP Antikörper (AA 320-400)

Produktnummer ABIN7227732

Der Kaninchen Polyklonal anti-CD2AP Antikörper wird verwendet zum Nachweis von CD2AP in Proben von Human und Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für CD2AP Antikörper (AA 320-400) (ABIN7227732)

Target: CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD2AP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-CD2AP Antikörper

Bindungsspezifität: AA 320-400

Verwendungszweck: Rabbit Anti-CD2AP Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of CD2AP protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CD2AP protein at AA range: 320-400

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu CD2AP

Target: CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))

Andere Bezeichnung: CD2AP

Hintergrund: CD2-associated protein, Adapter protein CMS, Cas ligand with multiple SH3 domainsCD2AP (CD2 Associated Protein) encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of CD2AP is implicated in susceptibility to glomerular disease. CD2AP is a Protein Coding gene. Diseases associated with CD2AP include Glomerulosclerosis, Focal Segmental, 3 and Sporadic Idiopathic Steroid-Resistant Nephrotic Syndrome With Focal Segmental Hyalinosis.

Molekulargewicht: 70kD

Gen-ID: 23607

UniProt: Q9Y5K6